Haufinyane tjena, China State Food and Drug Administration (SFDA) e amohetse semmuso ts'ebeliso ea papatso ea lijocimab (PCSK-9 Monoclonal antibody e entsoeng ke INNOVENT BIOLOGICS,INC), INC bakeng sa kalafo ea hypercholesterolemia ea mantlha (ho kenyeletsoa heterozygous family hypercholesterolemia le non-family hypercholesterolemia). hypercholesterolemia) le dyslipidemia e tsoakiloeng.Ena ke inhibitor ea pele ea PCSK-9 e iketselitseng ho etsa kopo ea ho bapatsa China.
Tafolecimab ke lithethefatsi tse ncha tsa biologic tse ikemetseng tse entsoeng ke INNOVENT BIOLOGICS, INC. IgG2 human monoclonal antibody ka ho khetheha e tlama PCSK-9 ho eketsa maemo a LDLR ka ho fokotsa PCSK-9-mediated endocytosis, kahoo e eketsa ho felisoa ha LDL-C le ho fokotsa maemo a LDL-C.
Lilemong tsa morao tjena, ho ata ha dyslipidemia ho eketsehile haholo Chaena.Ho ata ha lefu la dyslipidemia le hypercholesterolemia ho batho ba baholo ke 40.4% le 26.3% ka ho latellana.Ho latela tlaleho ea 2020 e mabapi le Bophelo bo Botle ba Mafu le Mafu Chaena, sekhahla sa kalafo le taolo ea dyslipidemia ho batho ba baholo se ntse se le maemong a tlase, mme sekhahla sa ho latela LDL-C sa bakuli ba dyslipidemia ha se khotsofatse le ho feta.
Pejana, li-statins e ne e le kalafo ea mantlha ea hypercholesterolemia Chaena, empa bakuli ba bangata ba ne ba ntse ba hloleha ho fihlela sepheo sa kalafo sa phokotso ea LDL-C kamora kalafo.Papatso ea PCSK-9 e tlisitse katleho e ntle ho bakuli.
Ho romelloa ha thekisocimab ho tsoa ho INNOVENT BIOLOGICS, INC ho ipapisitse le liphetho tsa liteko tse tharo tsa bongaka tse ngolisitsoeng molemong oa demokrasi, E na le boemo bo botle ba polokeho ka kakaretso, bo ts'oanang le litšobotsi tsa polokeho ea lihlahisoa tse rekisitsoeng, 'me e fihletse nako e telele (libeke tse ling le tse ling tse 6) tsa tsamaiso.Liphetho tsa thuto ea CREDIT-2 li amohetsoe ke Seboka sa Selemo le Selemo sa 2022 sa American College of Cardiology (ACC) e le ntho e sa utloahaleng le e phatlalalitsoeng inthaneteng.
Haeba kopo e amohetsoe, e tla senya nako ea PCSK-9, Chaena e tla fetoha naha ea bone ho ba le PCSK-9 ka mor'a United States (Amgen), France (Sanofi) le Switzerland (Novartis).
Nako ea poso: Jul-04-2022